EndTB Clinical Trials Intern M/F


Médecins Sans Frontières, an international humanitarian medical association created in 1971, provides medical assistance to populations whose lives are threatened: mainly in the event of armed conflict, but also epidemics, pandemics, natural disasters or exclusion from care. The French section of MSF is present in around thirty countries.


endTB is a project that aims to provide access to new treatments for patients with multidrug-resistant tuberculosis (MDR-TB). The project is carried out in partnership, within a consortium (associating MSF, Partners in Health (PIH) and Interactive Research and Development (IRD)), a research partnership (associating Harvard Medical School (HMS), Institute of Tropical Medicine-Antwerp (ITM) and Epicenter) and an additional contract with the University of California, San Francisco (UCSF). The project is co-funded by Unitaid and some consortium partners.

You will be the Sponsor-level intern for both clinical trials:

– endTB for which 750 MDR-TB patients are now enrolled and which will end in 2023,

– endTB-Q for which one third of the 324 XDR-TB patients remains to be recruited and which will end in 2024.

The two clinical trials are conducted under the responsibility of MSF France as Sponsor in 11 sites spread over 6 countries: India (MSF project), Peru, Kazakhstan, Lesotho (PIH projects), Pakistan (IRD project) and Vietnam (UCSF project ).

Reporting to the Trials Manager, you will be part of the central operational team, comprising around fifteen people (Central Study Coordinators, Biostatistician, Data Manager, Clinical Trials Pharmacist, Tuberculosis Laboratory Experts, Pharmacovigilance Manager, Trials Assistant Clinics), divided between the various partners, some of whom are based in Paris.

You will support the central operational team in clinical trial data management activities.

You will work in close collaboration with the 3 Central Study Coordinators (in charge of the daily monitoring of the country teams), Data Manager and Biostatistician.

Main activities of the intern

Work with Data Manager and Central Study Coordinators to assist with data cleaning activities:

  • Set up a process and follow-up tools until the resolution of requests sent by the operational team to the sites (e.g. requests raised for discrepancies between the case report form (CRF) and the protocol, requests from reconciliations with laboratory results)
  • Evaluate the frequency of requests and propose resolutions to the most common requests
  • Support missing data reconciliation and manual data review

Support the central coordinators of the study at the local level:

  • Attend regular weekly calls between sites and Central Study Coordinators and support the writing and posting of meeting minutes

This list of activities can be adjusted.

Job requirements

We are looking for an intern interested in research in general, and clinical trials in particular.

To apply for this internship, you must be at least completing a Bac+4 or a Master 1 in a field of health or science. A trainee in the course of Bac+5 or Master 2 would also be welcome.

If your training or previous experience has provided you with a good understanding of international ethical and regulatory requirements for clinical research, this is an asset, but not a prerequisite.

Specifics of the position

Status: 6-month full-time internship, based in Paris. Compulsory internship agreement.

Conditions: Remuneration according to the level of studies (from 4.48 €/hour Bac +3 to 6.55 €/hour Bac +5 and more). Restaurant vouchers with a face value of €9 (60% covered by Médecins Sans Frontières). 50% of the public transport ticket is covered.

Desired start date: July 2022.

How to register

Please send your application (motivation letter and CV in English, mentioning your date of availability) until July 3, 2022 inclusive


Only candidates whose applications have been selected will be contacted.


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